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Bridges, Hannah R., Blaza, James N., Yin, Zhan, Chung, Injae, Pollak, Michael N., Hirst, Judy (2023) Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379 (6630) 351-357 doi:10.1126/science.ade3332

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Reference TypeJournal (article/letter/editorial)
TitleStructural basis of mammalian respiratory complex I inhibition by medicinal biguanides
JournalScience
AuthorsBridges, Hannah R.Author
Blaza, James N.Author
Yin, ZhanAuthor
Chung, InjaeAuthor
Pollak, Michael N.Author
Hirst, JudyAuthor
Year2023 (January 27)Volume379
Issue6630
PublisherAmerican Association for the Advancement of Science (AAAS)
DOIdoi:10.1126/science.ade3332Search in ResearchGate
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Mindat Ref. ID15693724Long-form Identifiermindat:1:5:15693724:7
GUID0
Full ReferenceBridges, Hannah R., Blaza, James N., Yin, Zhan, Chung, Injae, Pollak, Michael N., Hirst, Judy (2023) Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379 (6630) 351-357 doi:10.1126/science.ade3332
Plain TextBridges, Hannah R., Blaza, James N., Yin, Zhan, Chung, Injae, Pollak, Michael N., Hirst, Judy (2023) Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379 (6630) 351-357 doi:10.1126/science.ade3332
In(2023, January) Science Vol. 379 (6630) American Association for the Advancement of Science (AAAS)

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Jones, Andrew J. Y., Blaza, James N., Bridges, Hannah R., May, Benjamin, Moore, Anthony L., Hirst, Judy (2016) A Self-Assembled Respiratory Chain that Catalyzes NADH Oxidation by Ubiquinone-10 Cycling between Complex I and the Alternative Oxidase. Angewandte Chemie, 128 (2). 738-741 doi:10.1002/ange.201507332
Wright, John J., Biner, Olivier, Chung, Injae, Burger, Nils, Bridges, Hannah R., Hirst, Judy (2022) Reverse Electron Transfer by Respiratory Complex I Catalyzed in a Modular Proteoliposome System. Journal of the American Chemical Society, 144 (15) 6791-6801 doi:10.1021/jacs.2c00274
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Jones, Andrew J. Y., Blaza, James N., Bridges, Hannah R., May, Benjamin, Moore, Anthony L., Hirst, Judy (2016) A Self-Assembled Respiratory Chain that Catalyzes NADH Oxidation by Ubiquinone-10 Cycling between Complex I and the Alternative Oxidase. Angewandte Chemie International Edition, 55 (2). 728-731 doi:10.1002/anie.201507332
Blaza, James N., Bridges, Hannah R., Aragão, David, Dunn, Elyse A., Heikal, Adam, Cook, Gregory M., Nakatani, Yoshio, Hirst, Judy (2017) The mechanism of catalysis by type-II NADH:quinone oxidoreductases. Scientific Reports, 7. doi:10.1038/srep40165
Grba, Daniel N., Wright, John J., Yin, Zhan, Fisher, William, Hirst, Judy (2024) Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384 (6701) 1247-1253 doi:10.1126/science.ado2075
Ivanov, Bozhidar S., Bridges, Hannah R., Jarman, Owen D., Hirst, Judy (2024) Structure of the turnover-ready state of an ancestral respiratory complex I. Nature Communications, 15 (1). doi:10.1038/s41467-024-53679-3
Vinothkumar, Kutti R., Zhu, Jiapeng, Hirst, Judy (2014) Architecture of mammalian respiratory complex I. Nature, 515 (7525). 80-84 doi:10.1038/nature13686
Zhu, Jiapeng, Vinothkumar, Kutti R., Hirst, Judy (2016) Structure of mammalian respiratory complex I. Nature, 536 (7616). 354-358 doi:10.1038/nature19095
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