Watch the Dallas Symposium LIVE, and fundraiser auction
Ticket proceeds support mindat.org! - click here...
Log InRegister
Quick Links : The Mindat ManualThe Rock H. Currier Digital LibraryMindat Newsletter [Free Download]
Home PageAbout MindatThe Mindat ManualHistory of MindatCopyright StatusWho We AreContact UsAdvertise on Mindat
Donate to MindatCorporate SponsorshipSponsor a PageSponsored PagesMindat AdvertisersAdvertise on Mindat
Learning CenterWhat is a mineral?The most common minerals on earthInformation for EducatorsMindat ArticlesThe ElementsThe Rock H. Currier Digital LibraryGeologic Time
Minerals by PropertiesMinerals by ChemistryAdvanced Locality SearchRandom MineralRandom LocalitySearch by minIDLocalities Near MeSearch ArticlesSearch GlossaryMore Search Options
Search For:
Mineral Name:
Locality Name:
Keyword(s):
 
The Mindat ManualAdd a New PhotoRate PhotosLocality Edit ReportCoordinate Completion ReportAdd Glossary Item
Mining CompaniesStatisticsUsersMineral MuseumsClubs & OrganizationsMineral Shows & EventsThe Mindat DirectoryDevice SettingsThe Mineral Quiz
Photo SearchPhoto GalleriesSearch by ColorNew Photos TodayNew Photos YesterdayMembers' Photo GalleriesPast Photo of the Day GalleryPhotography

Reich, S. H., Melnick, M., Davies, J. F., Appelt, K., Lewis, K. K., Fuhry, M. A., Pino, M., Trippe, A. J., Nguyen, D., Dawson, H. (1995) Protein structure-based design of potent orally bioavailable, nonpeptide inhibitors of human immunodeficiency virus protease. Proceedings of the National Academy of Sciences, 92 (8) 3298-3302 doi:10.1073/pnas.92.8.3298

Advanced
   -   Only viewable:
Reference TypeJournal (article/letter/editorial)
TitleProtein structure-based design of potent orally bioavailable, nonpeptide inhibitors of human immunodeficiency virus protease.
JournalProceedings of the National Academy of Sciences
AuthorsReich, S. H.Author
Melnick, M.Author
Davies, J. F.Author
Appelt, K.Author
Lewis, K. K.Author
Fuhry, M. A.Author
Pino, M.Author
Trippe, A. J.Author
Nguyen, D.Author
Dawson, H.Author
Year1995 (April 11)Volume92
Issue8
PublisherProceedings of the National Academy of Sciences
DOIdoi:10.1073/pnas.92.8.3298Search in ResearchGate
Generate Citation Formats
Mindat Ref. ID1569787Long-form Identifiermindat:1:5:1569787:7
GUID0
Full ReferenceReich, S. H., Melnick, M., Davies, J. F., Appelt, K., Lewis, K. K., Fuhry, M. A., Pino, M., Trippe, A. J., Nguyen, D., Dawson, H. (1995) Protein structure-based design of potent orally bioavailable, nonpeptide inhibitors of human immunodeficiency virus protease. Proceedings of the National Academy of Sciences, 92 (8) 3298-3302 doi:10.1073/pnas.92.8.3298
Plain TextReich, S. H., Melnick, M., Davies, J. F., Appelt, K., Lewis, K. K., Fuhry, M. A., Pino, M., Trippe, A. J., Nguyen, D., Dawson, H. (1995) Protein structure-based design of potent orally bioavailable, nonpeptide inhibitors of human immunodeficiency virus protease. Proceedings of the National Academy of Sciences, 92 (8) 3298-3302 doi:10.1073/pnas.92.8.3298
In(1995, April) Proceedings of the National Academy of Sciences Vol. 92 (8) Proceedings of the National Academy of Sciences

See Also

These are possibly similar items as determined by title/reference text matching only.

DesJarlais, R. L., Seibel, G. L., Kuntz, I. D., Furth, P. S., Alvarez, J. C., Ortiz de Montellano, P. R., DeCamp, D. L., Babe, L. M., Craik, C. S. (1990) Structure-based design of nonpeptide inhibitors specific for the human immunodeficiency virus 1 protease. Proceedings of the National Academy of Sciences, 87 (17) 6644-6648 doi:10.1073/pnas.87.17.6644
Bartz, S. R., Hohenwalter, E., Hu, M. K., Rich, D. H., Malkovsky, M. (1995) Inhibition of human immunodeficiency virus replication by nonimmunosuppressive analogs of cyclosporin A. Proceedings of the National Academy of Sciences, 92 (12) 5381-5385 doi:10.1073/pnas.92.12.5381
Kempf, D. J., Marsh, K. C., Denissen, J. F., McDonald, E., Vasavanonda, S., Flentge, C. A., Green, B. E., Fino, L., Park, C. H., Kong, X. P. (1995) ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans. Proceedings of the National Academy of Sciences, 92 (7) 2484-2488 doi:10.1073/pnas.92.7.2484
Vacca, J. P., Dorsey, B. D., Schleif, W. A., Levin, R. B., McDaniel, S. L., Darke, P. L., Zugay, J., Quintero, J. C., Blahy, O. M., Roth, E. (1994) L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitor. Proceedings of the National Academy of Sciences, 91 (9) 4096-4100 doi:10.1073/pnas.91.9.4096
Matsukura, M., Shinozuka, K., Zon, G., Mitsuya, H., Reitz, M., Cohen, J. S., Broder, S. (1987) Phosphorothioate analogs of oligodeoxynucleotides: inhibitors of replication and cytopathic effects of human immunodeficiency virus. Proceedings of the National Academy of Sciences, 84 (21) 7706-7710 doi:10.1073/pnas.84.21.7706
Babe, L. M., Rose, J., Craik, C. S. (1995) Trans-dominant inhibitory human immunodeficiency virus type 1 protease monomers prevent protease activation and virion maturation. Proceedings of the National Academy of Sciences, 92 (22) 10069-10073 doi:10.1073/pnas.92.22.10069
Patchett, A. A., Nargund, R. P., Tata, J. R., Chen, M. H., Barakat, K. J., Johnston, D. B., Cheng, K., Chan, W. W., Butler, B., Hickey, G. (1995) Design and biological activities of L-163,191 (MK-0677): a potent, orally active growth hormone secretagogue. Proceedings of the National Academy of Sciences, 92 (15) 7001-7005 doi:10.1073/pnas.92.15.7001
Schwartz, D. H., Sharma, U. K., Perlman, E. J., Blakemore, K. (1995) Adherence of human immunodeficiency virus-infected lymphocytes to fetal placental cells: a model of maternal --> fetal transmission. Proceedings of the National Academy of Sciences, 92 (4) 978-982 doi:10.1073/pnas.92.4.978
Nasioulas, G., Hughes, S. H., Felber, B. K., Whitcomb, J. M. (1995) Production of avian leukosis virus particles in mammalian cells can be mediated by the interaction of the human immunodeficiency virus protein Rev and the Rev-responsive element. Proceedings of the National Academy of Sciences, 92 (25) 11940-11944 doi:10.1073/pnas.92.25.11940
Fesen, M. R., Kohn, K. W., Leteurtre, F., Pommier, Y. (1993) Inhibitors of human immunodeficiency virus integrase. Proceedings of the National Academy of Sciences, 90 (6) 2399-2403 doi:10.1073/pnas.90.6.2399
Swain, A. L., Miller, M. M., Green, J., Rich, D. H., Schneider, J., Kent, S. B., Wlodawer, A. (1990) X-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitor. Proceedings of the National Academy of Sciences, 87 (22) 8805-8809 doi:10.1073/pnas.87.22.8805
 
and/or  
Mindat.org is an outreach project of the Hudson Institute of Mineralogy, a 501(c)(3) not-for-profit organization.
Copyright © mindat.org and the Hudson Institute of Mineralogy 1993-2025, except where stated. Most political location boundaries are Β© OpenStreetMap contributors. Mindat.org relies on the contributions of thousands of members and supporters. Founded in 2000 by Jolyon Ralph.
To cite: Ralph, J., Von Bargen, D., Martynov, P., Zhang, J., Que, X., Prabhu, A., Morrison, S. M., Li, W., Chen, W., & Ma, X. (2025). Mindat.org: The open access mineralogy database to accelerate data-intensive geoscience research. American Mineralogist, 110(6), 833–844. doi:10.2138/am-2024-9486.
Privacy Policy - Terms & Conditions - Contact Us / DMCA issues - Report a bug/vulnerability Current server date and time: August 23, 2025 15:20:28
Go to top of page