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Jayakumar, A., Chirala, S. S., Wakil, S. J. (1997) Human fatty acid synthase: Assembling recombinant halves of the fatty acid synthase subunit protein reconstitutes enzyme activity. Proceedings of the National Academy of Sciences, 94 (23) 12326-12330 doi:10.1073/pnas.94.23.12326

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Reference TypeJournal (article/letter/editorial)
TitleHuman fatty acid synthase: Assembling recombinant halves of the fatty acid synthase subunit protein reconstitutes enzyme activity
JournalProceedings of the National Academy of Sciences
AuthorsJayakumar, A.Author
Chirala, S. S.Author
Wakil, S. J.Author
Year1997 (November 11)Volume94
Issue23
PublisherProceedings of the National Academy of Sciences
DOIdoi:10.1073/pnas.94.23.12326Search in ResearchGate
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Mindat Ref. ID1596970Long-form Identifiermindat:1:5:1596970:1
GUID0
Full ReferenceJayakumar, A., Chirala, S. S., Wakil, S. J. (1997) Human fatty acid synthase: Assembling recombinant halves of the fatty acid synthase subunit protein reconstitutes enzyme activity. Proceedings of the National Academy of Sciences, 94 (23) 12326-12330 doi:10.1073/pnas.94.23.12326
Plain TextJayakumar, A., Chirala, S. S., Wakil, S. J. (1997) Human fatty acid synthase: Assembling recombinant halves of the fatty acid synthase subunit protein reconstitutes enzyme activity. Proceedings of the National Academy of Sciences, 94 (23) 12326-12330 doi:10.1073/pnas.94.23.12326
In(1997, November) Proceedings of the National Academy of Sciences Vol. 94 (23) Proceedings of the National Academy of Sciences

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Chirala, S. S., Jayakumar, A., Gu, Z.-W., Wakil, S. J. (2001) Human fatty acid synthase: Role of interdomain in the formation of catalytically active synthase dimer. Proceedings of the National Academy of Sciences, 98 (6) 3104-3108 doi:10.1073/pnas.051635998
Chirala, S. S., Huang, W.-Y., Jayakumar, A., Sakai, K., Wakil, S. J. (1997) Animal fatty acid synthase: Functional mapping and cloning and expression of the domain I constituent activities. Proceedings of the National Academy of Sciences, 94 (11) 5588-5593 doi:10.1073/pnas.94.11.5588
Jayakumar, A., Huang, W.-Y., Raetz, B., Chirala, S. S., Wakil, S. J. (1996) Cloning and expression of the multifunctional human fatty acid synthase and its subdomains in Escherichia coli. Proceedings of the National Academy of Sciences, 93 (25) 14509-14514 doi:10.1073/pnas.93.25.14509
Jayakumar, A., Tai, M. H., Huang, W. Y., al-Feel, W., Hsu, M., Abu-Elheiga, L., Chirala, S. S., Wakil, S. J. (1995) Human fatty acid synthase: properties and molecular cloning. Proceedings of the National Academy of Sciences, 92 (19) 8695-8699 doi:10.1073/pnas.92.19.8695
Chakravarty, B., Gu, Z., Chirala, S. S., Wakil, S. J., Quiocho, F. A. (2004) Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain. Proceedings of the National Academy of Sciences, 101 (44) 15567-15572 doi:10.1073/pnas.0406901101
Xiong, S., Chirala, S. S., Hsu, M. H., Wakil, S. J. (1998) Identification of thyroid hormone response elements in the human fatty acid synthase promoter. Proceedings of the National Academy of Sciences, 95 (21) 12260-12265 doi:10.1073/pnas.95.21.12260
Xiong, S., Chirala, S. S., Wakil, S. J. (2000) Sterol regulation of human fatty acid synthase promoter I requires nuclear factor-Y- and Sp-1-binding sites. Proceedings of the National Academy of Sciences, 97 (8) 3948-3953 doi:10.1073/pnas.040574197
Chirala, S. S. (1992) Coordinated regulation and inositol-mediated and fatty acid-mediated repression of fatty acid synthase genes in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences, 89 (21) 10232-10236 doi:10.1073/pnas.89.21.10232
Chirala, S. S., Chang, H., Matzuk, M., Abu-Elheiga, L., Mao, J., Mahon, K., Finegold, M., Wakil, S. J. (2003) Fatty acid synthesis is essential in embryonic development: Fatty acid synthase null mutants and most of the heterozygotes die in utero. Proceedings of the National Academy of Sciences, 100 (11) 6358-6363 doi:10.1073/pnas.0931394100
Tai, M. H., Chirala, S. S., Wakil, S. J. (1993) Roles of Ser101, Asp236, and His237 in catalysis of thioesterase II and of the C-terminal region of the enzyme in its interaction with fatty acid synthase. Proceedings of the National Academy of Sciences, 90 (5) 1852-1856 doi:10.1073/pnas.90.5.1852
Brink, J., Ludtke, S. J., Yang, C.-Y., Gu, Z.-W., Wakil, S. J., Chiu, W. (2002) Quaternary structure of human fatty acid synthase by electron cryomicroscopy. Proceedings of the National Academy of Sciences, 99 (1) 138-143 doi:10.1073/pnas.012589499
 
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