Vote for your favorite mineral in #MinCup25! - Paddlewheelite vs. Mannardite
It's a battle of the tiny as bright green #paddlewheelite goes up against jet black #mannardite. Both are small yet mighty minerals, but only one can win!
Log InRegister
Quick Links : The Mindat ManualThe Rock H. Currier Digital LibraryMindat Newsletter [Free Download]
Home PageAbout MindatThe Mindat ManualHistory of MindatCopyright StatusWho We AreContact UsAdvertise on Mindat
Donate to MindatCorporate SponsorshipSponsor a PageSponsored PagesMindat AdvertisersAdvertise on Mindat
Learning CenterWhat is a mineral?The most common minerals on earthInformation for EducatorsMindat ArticlesThe ElementsThe Rock H. Currier Digital LibraryGeologic Time
Minerals by PropertiesMinerals by ChemistryAdvanced Locality SearchRandom MineralRandom LocalitySearch by minIDLocalities Near MeSearch ArticlesSearch GlossaryMore Search Options
Search For:
Mineral Name:
Locality Name:
Keyword(s):
 
The Mindat ManualAdd a New PhotoRate PhotosLocality Edit ReportCoordinate Completion ReportAdd Glossary Item
Mining CompaniesStatisticsUsersMineral MuseumsClubs & OrganizationsMineral Shows & EventsThe Mindat DirectoryDevice SettingsThe Mineral Quiz
Photo SearchPhoto GalleriesSearch by ColorNew Photos TodayNew Photos YesterdayMembers' Photo GalleriesPast Photo of the Day GalleryPhotography

Haspel, Nurit, Jang, Hyunbum, Nussinov, Ruth (2024) Allosteric Activation of RhoA Complexed with p115-RhoGEF Deciphered by Conformational Dynamics. Journal of Chemical Information and Modeling, 64 (3) 862-873 doi:10.1021/acs.jcim.3c01412

Advanced
   -   Only viewable:
Reference TypeJournal (article/letter/editorial)
TitleAllosteric Activation of RhoA Complexed with p115-RhoGEF Deciphered by Conformational Dynamics
JournalJournal of Chemical Information and Modeling
AuthorsHaspel, NuritAuthor
Jang, HyunbumAuthor
Nussinov, RuthAuthor
Year2024 (February 12)Volume64
Issue3
PublisherAmerican Chemical Society (ACS)
DOIdoi:10.1021/acs.jcim.3c01412Search in ResearchGate
Generate Citation Formats
Mindat Ref. ID17156790Long-form Identifiermindat:1:5:17156790:0
GUID0
Full ReferenceHaspel, Nurit, Jang, Hyunbum, Nussinov, Ruth (2024) Allosteric Activation of RhoA Complexed with p115-RhoGEF Deciphered by Conformational Dynamics. Journal of Chemical Information and Modeling, 64 (3) 862-873 doi:10.1021/acs.jcim.3c01412
Plain TextHaspel, Nurit, Jang, Hyunbum, Nussinov, Ruth (2024) Allosteric Activation of RhoA Complexed with p115-RhoGEF Deciphered by Conformational Dynamics. Journal of Chemical Information and Modeling, 64 (3) 862-873 doi:10.1021/acs.jcim.3c01412
In(2024, February) Journal of Chemical Information and Modeling Vol. 64 (3) American Chemical Society (ACS)

See Also

These are possibly similar items as determined by title/reference text matching only.

Liu, Yonglan, Zhang, Wengang, Jang, Hyunbum, Nussinov, Ruth (2025) mTOR Variants Activation Discovers PI3K-like Cryptic Pocket, Expanding Allosteric, Mutant-Selective Inhibitor Designs. Journal of Chemical Information and Modeling, 65 (2). doi:10.1021/acs.jcim.4c02022
Xu, Liang, Jang, Hyunbum, Nussinov, Ruth (2024) Capturing Autoinhibited PDK1 Reveals the Linker’s Regulatory Role, Informing Innovative Inhibitor Design. Journal of Chemical Information and Modeling, 64 (19). doi:10.1021/acs.jcim.4c01392
Liu, Yonglan, Zhang, Mingzhen, Jang, Hyunbum, Nussinov, Ruth (2024) The allosteric mechanism of mTOR activation can inform bitopic inhibitor optimization. Chemical Science, 15 (3) 1003-1017 doi:10.1039/d3sc04690g
Zanuy, David, Ballano, Gema, Jiménez, Ana I., Casanovas, Jordi, Haspel, Nurit, Cativiela, Carlos, Curcó, David, Nussinov, Ruth, Alemán, Carlos (2009) Protein Segments with Conformationally Restricted Amino Acids Can Control Supramolecular Organization at the Nanoscale. Journal of Chemical Information and Modeling, 49 (7) 1623-1629 doi:10.1021/ci9001487
Nussinov, Ruth, Zhang, Mingzhen, Maloney, Ryan, Liu, Yonglan, Tsai, Chung-Jung, Jang, Hyunbum (2022) Allostery: Allosteric Cancer Drivers and Innovative Allosteric Drugs. Journal of Molecular Biology, 434 (17) 167569 doi:10.1016/j.jmb.2022.167569
Zhang, Mingzhen, Jang, Hyunbum, Nussinov, Ruth (2019) The mechanism of PI3Kα activation at the atomic level. Chemical Science, 10. 3671-3680 doi:10.1039/c8sc04498h
Grudzien, Patrick, Jang, Hyunbum, Leschinsky, Nicholas, Nussinov, Ruth, Gaponenko, Vadim (2022) Conformational Dynamics Allows Sampling of an “Active-like” State by Oncogenic K-Ras-GDP. Journal of Molecular Biology, 434 (17) 167695 doi:10.1016/j.jmb.2022.167695
Zhang, Mingzhen, Maloney, Ryan, Jang, Hyunbum, Nussinov, Ruth (2021) The mechanism of Raf activation through dimerization. Chemical Science, 12 (47) 15609-15619 doi:10.1039/d1sc03444h
Lu, Shaoyong, Jang, Hyunbum, Muratcioglu, Serena, Gursoy, Attila, Keskin, Ozlem, Nussinov, Ruth, Zhang, Jian (2016) Ras Conformational Ensembles, Allostery, and Signaling. Chemical Reviews, 116 (11) 6607-6665 doi:10.1021/acs.chemrev.5b00542
Lin, Yuan, Ramelot, Theresa A., Senyuz, Simge, Gursoy, Attila, Jang, Hyunbum, Nussinov, Ruth, Keskin, Ozlem, Zheng, Yi (2024) Tumor-derived RHOA mutants interact with effectors in the GDP-bound state. Nature Communications, 15 (1). doi:10.1038/s41467-024-51445-z
Zhang, Mingzhen, Jang, Hyunbum, Nussinov, Ruth (2019) The structural basis for Ras activation of PI3Kα lipid kinase. Physical Chemistry Chemical Physics, 21 (22). 12021-12028 doi:10.1039/c9cp00101h
 
and/or  
Mindat.org is an outreach project of the Hudson Institute of Mineralogy, a 501(c)(3) not-for-profit organization.
Copyright © mindat.org and the Hudson Institute of Mineralogy 1993-2025, except where stated. Most political location boundaries are © OpenStreetMap contributors. Mindat.org relies on the contributions of thousands of members and supporters. Founded in 2000 by Jolyon Ralph.
To cite: Ralph, J., Von Bargen, D., Martynov, P., Zhang, J., Que, X., Prabhu, A., Morrison, S. M., Li, W., Chen, W., & Ma, X. (2025). Mindat.org: The open access mineralogy database to accelerate data-intensive geoscience research. American Mineralogist, 110(6), 833–844. doi:10.2138/am-2024-9486.
Privacy Policy - Terms & Conditions - Contact Us / DMCA issues - Report a bug/vulnerability Current server date and time: September 16, 2025 23:23:29
Go to top of page