Log InRegister
Quick Links : The Mindat ManualThe Rock H. Currier Digital LibraryMindat Newsletter [Free Download]
Home PageAbout MindatThe Mindat ManualHistory of MindatCopyright StatusWho We AreContact UsAdvertise on Mindat
Donate to MindatCorporate SponsorshipSponsor a PageSponsored PagesMindat AdvertisersAdvertise on Mindat
Learning CenterWhat is a mineral?The most common minerals on earthInformation for EducatorsMindat ArticlesThe ElementsThe Rock H. Currier Digital LibraryGeologic Time
Minerals by PropertiesMinerals by ChemistryAdvanced Locality SearchRandom MineralRandom LocalitySearch by minIDLocalities Near MeSearch ArticlesSearch GlossaryMore Search Options
Search For:
Mineral Name:
Locality Name:
Keyword(s):
 
The Mindat ManualAdd a New PhotoRate PhotosLocality Edit ReportCoordinate Completion ReportAdd Glossary Item
Mining CompaniesStatisticsUsersMineral MuseumsClubs & OrganizationsMineral Shows & EventsThe Mindat DirectoryDevice SettingsThe Mineral Quiz
Photo SearchPhoto GalleriesSearch by ColorNew Photos TodayNew Photos YesterdayMembers' Photo GalleriesPast Photo of the Day GalleryPhotography

Shan, Yibing, Kim, Eric T., Eastwood, Michael P., Dror, Ron O., Seeliger, Markus A., Shaw, David E. (2011) How Does a Drug Molecule Find Its Target Binding Site?. Journal Of The American Chemical Society, 133 (24) 9181-9183 doi:10.1021/ja202726y

Advanced
   -   Only viewable:
Reference TypeJournal (article/letter/editorial)
TitleHow Does a Drug Molecule Find Its Target Binding Site?
JournalJournal Of The American Chemical Society
AuthorsShan, YibingAuthor
Kim, Eric T.Author
Eastwood, Michael P.Author
Dror, Ron O.Author
Seeliger, Markus A.Author
Shaw, David E.Author
Year2011 (June 22)Volume133
Issue24
PublisherAmerican Chemical Society (ACS)
DOIdoi:10.1021/ja202726ySearch in ResearchGate
Generate Citation Formats
Mindat Ref. ID1736214Long-form Identifiermindat:1:5:1736214:2
GUID0
Full ReferenceShan, Yibing, Kim, Eric T., Eastwood, Michael P., Dror, Ron O., Seeliger, Markus A., Shaw, David E. (2011) How Does a Drug Molecule Find Its Target Binding Site?. Journal Of The American Chemical Society, 133 (24) 9181-9183 doi:10.1021/ja202726y
Plain TextShan, Yibing, Kim, Eric T., Eastwood, Michael P., Dror, Ron O., Seeliger, Markus A., Shaw, David E. (2011) How Does a Drug Molecule Find Its Target Binding Site?. Journal Of The American Chemical Society, 133 (24) 9181-9183 doi:10.1021/ja202726y
In(2011, June) Journal Of The American Chemical Society Vol. 133 (24) American Chemical Society (ACS)

See Also

These are possibly similar items as determined by title/reference text matching only.

Shan, Yibing, Kim, Eric, Eastwood, Michael P., Dror, Ron O., Seeliger, Markus A., Shaw, David E. (2014) Correction to How Does a Drug Molecule Find its Target Binding Site?. Journal Of The American Chemical Society, 136 (8) 3320 doi:10.1021/ja500545u
Shan, Yibing, Klepeis, John L., Eastwood, Michael P., Dror, Ron O., Shaw, David E. (2005) Gaussian split Ewald: A fast Ewald mesh method for molecular simulation. The Journal of Chemical Physics, 122 (5). 54101pp. doi:10.1063/1.1839571
Foda, Zachariah H., Shan, Yibing, Kim, Eric T., Shaw, David E., Seeliger, Markus A. (2015) A dynamically coupled allosteric network underlies binding cooperativity in Src kinase. Nature Communications, 6. doi:10.1038/ncomms6939
Shan, Y., Seeliger, M. A., Eastwood, M. P., Frank, F., Xu, H., Jensen, M. O, Dror, R. O., Kuriyan, J., Shaw, D. E. (2009) A conserved protonation-dependent switch controls drug binding in the Abl kinase. Proceedings of the National Academy of Sciences, 106 (1) 139-144 doi:10.1073/pnas.0811223106
Dror, Ron O., Pan, Albert C., Arlow, Daniel H., Borhani, David W., Maragakis, Paul, Shan, Yibing, Xu, Huafeng, Shaw, David E. (2011) Pathway and mechanism of drug binding to G-protein-coupled receptors. Proceedings of the National Academy of Sciences, 108 (32) 13118-13123 doi:10.1073/pnas.1104614108
Ayaz, Pelin, Lyczek, Agatha, Paung, YiTing, Mingione, Victoria R., Iacob, Roxana E., de Waal, Parker W., Engen, John R., Seeliger, Markus A., Shan, Yibing, Shaw, David E. (2023) Structural mechanism of a drug-binding process involving a large conformational change of the protein target. Nature Communications, 14 (1) doi:10.1038/s41467-023-36956-5
Lippert, Ross A., Bowers, Kevin J., Dror, Ron O., Eastwood, Michael P., Gregersen, Brent A., Klepeis, John L., Kolossvary, Istvan, Shaw, David E. (2007) A common, avoidable source of error in molecular dynamics integrators. The Journal of Chemical Physics, 126 (4). 46101pp. doi:10.1063/1.2431176
Lippert, Ross A., Predescu, Cristian, Ierardi, Douglas J., Mackenzie, Kenneth M., Eastwood, Michael P., Dror, Ron O., Shaw, David E. (2013) Accurate and efficient integration for molecular dynamics simulations at constant temperature and pressure. The Journal of Chemical Physics, 139 (16). 164106pp. doi:10.1063/1.4825247
Shenfeld, Daniel K., Xu, Huafeng, Eastwood, Michael P., Dror, Ron O., Shaw, David E. (2009) Minimizing thermodynamic length to select intermediate states for free-energy calculations and replica-exchange simulations. Physical Review E, 80 (4) doi:10.1103/physreve.80.046705
Predescu, Cristian, Lippert, Ross A., Eastwood, Michael P., Ierardi, Douglas, Xu, Huafeng, Jensen, Morten Ø., Bowers, Kevin J., Gullingsrud, Justin, Rendleman, Charles A., Dror, Ron O., Shaw, David E. (2012) Computationally efficient molecular dynamics integrators with improved sampling accuracy. Molecular Physics, 110. 967-983 doi:10.1080/00268976.2012.681311
Shenfeld, Daniel K., Xu, Huafeng, Eastwood, Michael P., Dror, Ron O., Shaw, David E. (2009) Publisher's Note: Minimizing thermodynamic length to select intermediate states for free-energy calculations and replica-exchange simulations [Phys. Rev. E80, 046705 (2009)]. Physical Review E, 80 (4) doi:10.1103/physreve.80.049904
 
and/or  
Mindat.org is an outreach project of the Hudson Institute of Mineralogy, a 501(c)(3) not-for-profit organization.
Copyright © mindat.org and the Hudson Institute of Mineralogy 1993-2025, except where stated. Most political location boundaries are Β© OpenStreetMap contributors. Mindat.org relies on the contributions of thousands of members and supporters. Founded in 2000 by Jolyon Ralph.
To cite: Ralph, J., Von Bargen, D., Martynov, P., Zhang, J., Que, X., Prabhu, A., Morrison, S. M., Li, W., Chen, W., & Ma, X. (2025). Mindat.org: The open access mineralogy database to accelerate data-intensive geoscience research. American Mineralogist, 110(6), 833–844. doi:10.2138/am-2024-9486.
Privacy Policy - Terms & Conditions - Contact Us / DMCA issues - Report a bug/vulnerability Current server date and time: August 30, 2025 14:40:32
Go to top of page