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Velkova, Aleksandra, Tatarek-Nossol, Marianna, Andreetto, Erika, Kapurniotu, Aphrodite (2008) Exploiting Cross-Amyloid Interactions To Inhibit Protein Aggregation but not Function: Nanomolar Affinity Inhibition of Insulin Aggregation by an IAPP Mimic. Angewandte Chemie International Edition, 47 (37). 7114-7118 doi:10.1002/anie.200801499

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Reference TypeJournal (article/letter/editorial)
TitleExploiting Cross-Amyloid Interactions To Inhibit Protein Aggregation but not Function: Nanomolar Affinity Inhibition of Insulin Aggregation by an IAPP Mimic
JournalAngewandte Chemie International Edition
AuthorsVelkova, AleksandraAuthor
Tatarek-Nossol, MariannaAuthor
Andreetto, ErikaAuthor
Kapurniotu, AphroditeAuthor
Year2008 (September 1)Volume47
Issue37
PublisherWiley
DOIdoi:10.1002/anie.200801499Search in ResearchGate
Generate Citation Formats
Mindat Ref. ID8586364Long-form Identifiermindat:1:5:8586364:0
GUID0
Full ReferenceVelkova, Aleksandra, Tatarek-Nossol, Marianna, Andreetto, Erika, Kapurniotu, Aphrodite (2008) Exploiting Cross-Amyloid Interactions To Inhibit Protein Aggregation but not Function: Nanomolar Affinity Inhibition of Insulin Aggregation by an IAPP Mimic. Angewandte Chemie International Edition, 47 (37). 7114-7118 doi:10.1002/anie.200801499
Plain TextVelkova, Aleksandra, Tatarek-Nossol, Marianna, Andreetto, Erika, Kapurniotu, Aphrodite (2008) Exploiting Cross-Amyloid Interactions To Inhibit Protein Aggregation but not Function: Nanomolar Affinity Inhibition of Insulin Aggregation by an IAPP Mimic. Angewandte Chemie International Edition, 47 (37). 7114-7118 doi:10.1002/anie.200801499
In(2008, September) Angewandte Chemie International Edition Vol. 47 (37) Wiley

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Velkova, Aleksandra, Tatarek-Nossol, Marianna, Andreetto, Erika, Kapurniotu, Aphrodite (2008) Amyloid-Kreuzwechselwirkung zur Inhibierung der Proteinaggregation, nicht aber der Proteinfunktion: Inhibierung der Insulinaggregation im nanomolaren Bereich durch ein IAPP-Mimetikum. Angewandte Chemie, 120 (37). 7222-7227 doi:10.1002/ange.200801499
Yan, Li-Mei, Velkova, Aleksandra, Tatarek-Nossol, Marianna, Andreetto, Erika, Kapurniotu, Aphrodite (2007) IAPP Mimic Blocks Aβ Cytotoxic Self-Assembly: Cross-Suppression of Amyloid Toxicity of Aβ and IAPP Suggests a Molecular Link between Alzheimer's Disease and Type II Diabetes. Angewandte Chemie International Edition, 46 (8). 1246-1252 doi:10.1002/anie.200604056
Andreetto, Erika, Yan, Li-Mei, Tatarek-Nossol, Marianna, Velkova, Aleksandra, Frank, Ronald, Kapurniotu, Aphrodite (2010) Identification of Hot Regions of the Aβ-IAPP Interaction Interface as High-Affinity Binding Sites in both Cross- and Self-Association. Angewandte Chemie International Edition, 49 (17). 3081-3085 doi:10.1002/anie.200904902
Yan, Li-Mei, Velkova, Aleksandra, Tatarek-Nossol, Marianna, Andreetto, Erika, Kapurniotu, Aphrodite (2007) Ein IAPP-Mimetikum blockiert die zytotoxische Aggregation von Aβ – die Kreuzunterdrückung der Amyloidtoxizität von Aβ und IAPP deutet auf einen molekularen Zusammenhang zwischen Alzheimer-Krankheit und Typ-II-Diabetes hin. Angewandte Chemie, 119 (8). 1268-1274 doi:10.1002/ange.200604056
Andreetto, Erika, Yan, Li-Mei, Tatarek-Nossol, Marianna, Velkova, Aleksandra, Frank, Ronald, Kapurniotu, Aphrodite (2010) Hot-Spot-Regionen der Aβ-IAPP-Wechselwirkungsdomänen als hochaffine Bindungsstellen bei Kreuz- und Selbstassoziation. Angewandte Chemie, 122 (17). 3146-3151 doi:10.1002/ange.200904902
Yan, Li-Mei, Velkova, Aleksandra, Tatarek-Nossol, Marianna, Rammes, Gerhard, Sibaev, Andrei, Andreetto, Erika, Kracklauer, Michael, Bakou, Maria, Malideli, Eleni, Göke, Burkhard, Schirra, Jörg, Storr, Martin, Kapurniotu, Aphrodite (2013) Selectively N-Methylated Soluble IAPP Mimics as Potent IAPP Receptor Agonists and Nanomolar Inhibitors of Cytotoxic Self-Assembly of Both IAPP and Aβ40. Angewandte Chemie International Edition, 52 (39). 10378-10383 doi:10.1002/anie.201302840
Yan, Li-Mei, Tatarek-Nossol, Marianna, Velkova, Aleksandra, Kazantzis, Athanasios, Kapurniotu, Aphrodite (2006) Design of a mimic of nonamyloidogenic and bioactive human islet amyloid polypeptide (IAPP) as nanomolar affinity inhibitor of IAPP cytotoxic fibrillogenesis. Proceedings of the National Academy of Sciences, 103 (7) 2046-2051 doi:10.1073/pnas.0507471103
Yan, Li-Mei, Velkova, Aleksandra, Tatarek-Nossol, Marianna, Rammes, Gerhard, Sibaev, Andrei, Andreetto, Erika, Kracklauer, Michael, Bakou, Maria, Malideli, Eleni, Göke, Burkhard, Schirra, Jörg, Storr, Martin, Kapurniotu, Aphrodite (2013) Selektiv N-methylierte lösliche IAPP-Mimetika als potente IAPP-Rezeptoragonisten und nanomolare Inhibitoren der Selbstassoziation von IAPP und Aβ40. Angewandte Chemie, 125 (39). 10569-10574 doi:10.1002/ange.201302840
Andreetto, Erika, Malideli, Eleni, Yan, Li-Mei, Kracklauer, Michael, Farbiarz, Karine, Tatarek-Nossol, Marianna, Rammes, Gerhard, Prade, Elke, Neumüller, Tatjana, Caporale, Andrea, Spanopoulou, Anna, Bakou, Maria, Reif, Bernd, Kapurniotu, Aphrodite (2015) A Hot-Segment-Based Approach for the Design of Cross-Amyloid Interaction Surface Mimics as Inhibitors of Amyloid Self-Assembly. Angewandte Chemie International Edition, 54 (44). 13095-13100 doi:10.1002/anie.201504973
Seeliger, Janine, Evers, Florian, Jeworrek, Christoph, Kapoor, Shobhna, Weise, Katrin, Andreetto, Erika, Tolan, Metin, Kapurniotu, Aphrodite, Winter, Roland (2012) Cross-Amyloid Interaction of Aβ and IAPP at Lipid Membranes. Angewandte Chemie International Edition, 51 (3). 679-683 doi:10.1002/anie.201105877
Grudzielanek, Stefan, Velkova, Aleksandra, Shukla, Anuj, Smirnovas, Vytautas, Tatarek-Nossol, Marianna, Rehage, Heinz, Kapurniotu, Aphrodite, Winter, Roland (2007) Cytotoxicity of Insulin within its Self-assembly and Amyloidogenic Pathways. Journal of Molecular Biology, 370 (2). 372-384 doi:10.1016/j.jmb.2007.04.053
 
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